Abstract: Elderly patients with frailty and multiple comorbidities increasingly require mitral valve surgery. This includes patients who have previously undergone surgery with a tissue valve, which may deteriorate over time and require replacement. These cases are considered high-risk. There is growing interest in performing valve replacements using minimally invasive techniques, including access via the groin. However, such approaches are not always... [...] Read more

Abstract: Multivalvular heart disease represents a less explored domain within cardiovascular surgery. In patients with aortic stenosis (AS) undergoing surgical or transcatheter aortic valve replacement (TAVR), the prevalence of moderate to severe mitral regurgitation (MR) ranges from 8% to 33%. Among the most common presentations are patients with severe AS and clinically significant functional MR. In instances of moderate surgical risk, open-heart... [...] Read more

Abstract: Early detection of Congenital Hypothyroidism (CH) is crucial to prevent intellectual disability in affected neonates. Neonatal screening for CH typically involves measuring thyroid-stimulating hormone (TSH) and thyroxine (T4) levels, with methods varying between cord blood and venous blood sampling. This study aims to compare the efficacy and reliability of cord blood versus day 3 venous blood sampling in the screening for CH to inform best... [...] Read more

Abstract: Background and aim of the study: Minimally invasive approaches for aortic valve replacement (AVR) are clinically beneficial for patients but are more technically demanding for surgeons. Sutureless AVR is a new and minimally invasive approach. The study aim was to evaluate initial AVR outcomes in patients aged >75 years after setting up a sutureless minimally invasive surgery program. Methods: Between January 2014 and December 2015, a total... [...] Read more

Abstract: Background and Study Aims: Rheumatic heart disease (RHD) remains a leading cause of mitral valve disease globally, particularly in developing countries, where it poses a significant burden on cardiovascular health. Mitral valve repair (MVP) and replacement are the primary surgical interventions; however, the optimal selection between these procedures remains a subject of ongoing debate. This study aims to systematically review the clinical... [...] Read more

Abstract: Calcific aortic stenosis (AS) is the most common valvular heart disease requiring invasive intervention. While the implantation of an artificial heart valve restores normal intracardiac hemodynamics, baseline left ventricular (LV) parameters can significantly influence both early and long-term postoperative outcomes. It is well-established that patients with LV dilation experience worse outcomes after surgical or transcatheter treatment of... [...] Read more