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The Clinical Evaluation of Rheumatic Mitral Valve Repair
Abstract: Background and Study Aims: Rheumatic heart disease (RHD) remains a leading cause of mitral valve disease globally, particularly in developing countries, where it poses a significant burden on cardiovascular health. Mitral valve repair (MVP) and replacement are the primary surgical interventions; however, the optimal selection between these procedures remains a subject of ongoing debate. This study aims to systematically review the clinical... [...] Read more
The Bicuspid Aortic Valve Repair With External Or Subcommissural Annuloplasty – A 13-Year Experience
Abstract: Background and Aim of the Study: An incompetent bicuspid aortic valve (BAV) can be treated through valve replacement or repair using various surgical techniques. This study presents the outcomes of a 13-year single-surgeon experience in BAV repair and compares two annuloplasty techniques: external and subcommissural aortic annuloplasty. Materials and Methods: A total of 150 consecutive patients (111 males; mean age: 43.2 ± 17.5 years)... [...] Read more
Setting Up A Minimally Invasive Surgery Program: The Sutureless Solution
Abstract: Background and aim of the study: Minimally invasive approaches for aortic valve replacement (AVR) are clinically beneficial for patients but are more technically demanding for surgeons. Sutureless AVR is a new and minimally invasive approach. The study aim was to evaluate initial AVR outcomes in patients aged >75 years after setting up a sutureless minimally invasive surgery program. Methods: Between January 2014 and December 2015, a total... [...] Read more
Predictors And Correlators Of Acute Aortic Syndrome: A Critical Review Of Current Evidence
Abstract: Background: Acute Aortic Syndrome’s (AAS) is a group of acute emergencies that include aortic dissection, intramural haematoma, penetrating atherosclerotic ulcer, and impending or ruptured aortic aneurysms. Various precipitating factors have been associated with the development of AAS, but it is unclear whether these factors are correlators or predictors of the disease. A clear understanding of these elements could improve the diagnosis,... [...] Read more
Patient-Prosthesis Mismatch Rate When Theoretical Ideal Body Weight Is Taken Into Account
Abstract: Objectives: This study aimed to examine whether the projected patient-prosthesis mismatch (PPM) rate calculated using the ideal body weight of patients can theoretically show a significant improvement compared to the actual rate of PPM conventionally calculated with the actual body weight of patients. Methods: We retrospectively analysed 2827 patients who underwent aortic valve replacement over 10 years. The rate of PPM was evaluated by... [...] Read more
Outcomes of Mitral Valve Transcatheter Edge-To-Edge Repair In Patients With Chronic Kidney Disease: A Systematic Review And Meta-Analysis
Abstract: Background: Transcatheter edge-to-edge repair of the mitral valve (M-TEER) improves outcomes in patients with chronic severe symptomatic mitral valve regurgitation who are at high risk for surgical mitral valve repair or replacement. This systematic review and meta-analysis aimed to describe the outcomes of M-TEER in patients with moderate-to-severe (stage III; Group 1) chronic kidney diseases (CKD) and end-stage kidney disease (stages... [...] Read more
Management of Cardiogenic Shock in Mitral Valve Diseases: A Review Article
Abstract: Despite advances in the field of cardiology, cardiogenic shock (CS) remains a management dilemma with a high mortality rate. While most cases of CS are secondary to acute coronary syndrome (ACS), approximately one-fifth can be attributed to delayed mechanical complications of ACS, such as arrhythmia, cardiac tamponade, or valvular heart diseases. The coexistence of CS and mitral valve diseases (MVDs) further complicates clinical presentation,... [...] Read more
Long-Term Outcomes of Native Infective Endocarditis After Surgery: A Single-Centre Experience
Abstract: Objective: Infective endocarditis requires prompt recognition and treatment due to its high mortality and morbidity rates. Few studies compare long-term patient outcomes after mitral and aortic valve endocarditis surgery. Hence, we aim to assess this in our cohort. Methods: We included adult patients aged 18 and above who underwent surgery between April 2011 and April 2021 for first-time native aortic or mitral valve endocarditis in our... [...] Read more
Impact of the COVID-19 Pandemic on Surgical Outcomes of Native and Prosthetic Valve Endocarditis: A Retrospective Subanalysis
Abstract: Background and aim of the study: During the COVID-19 pandemic in Bavaria, surgical ICU resources were reallocated, and elective procedures were postponed, impacting the management of infective endocarditis (IE). This study evaluated early surgical outcomes in patients with native valve endocarditis (NVE) and prosthetic valve endocarditis (PVE) before and during the pandemic. Methods: We retrospectively analyzed 94 patients (66% male) treated... [...] Read more
Evaluating Neonatal Screening Methods for Congenital Hypothyroidism: A Comparative Analysis of Cord Blood and Venous Blood Sampling
Abstract: Early detection of Congenital Hypothyroidism (CH) is crucial to prevent intellectual disability in affected neonates. Neonatal screening for CH typically involves measuring thyroid-stimulating hormone (TSH) and thyroxine (T4) levels, with methods varying between cord blood and venous blood sampling. This study aims to compare the efficacy and reliability of cord blood versus day 3 venous blood sampling in the screening for CH to inform best... [...] Read more
Eptifibatide Induced Thrombocytopenia in Acute Coronary Syndrome: A Real-World Data
Abstract: Background: Eptifibatide is a known antiplatelet that is used in patients undergoing percutaneous coronary intervention for ACS, and it is proven to have a positive outcome. Despite thrombocytopenia not being reported in the pivotal trials, the emerging literature associated this link. We aim to further investigate this association and provide real-world data from a single centre. Methods: A retrospective study was conducted in Heart Hospital... [...] Read more
Comparative Outcomes of Medical, Percutaneous, and Surgical Treatments for Tricuspid Valve Endocarditis
Abstract: Background: Tricuspid valve endocarditis (TVE) remains a significant cause of morbidity and mortality worldwide. Given the considerable variation in presentation and severity, as well as ongoing advances in percutaneous and operative interventions, the optimal treatment strategy remains undetermined. This study aims to report the outcomes of medical management (MM), percutaneous mechanical aspiration (PMA), and surgical intervention in... [...] Read more
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