Open Access Article June 15, 2024

9 Pages

Patient-Prosthesis Mismatch Rate When Theoretical Ideal Body Weight Is Taken Into Account

Authors

Mirko Muretti1,* , Enoch Akowuah2 , Andrew Goodwin3

  1. The James Cook University
  2. James Cook University Hospital image/svg+xml
  3. The James Cook University Hospital
  4. * Author to whom correspondence should be addressed.

Journal of Heart Valve Disease Innovation 2024, 29(1), 06-14; https://doi.org/10.36923/jhvd.v29i1.206

Abstract

Objectives: This study aimed to examine whether the projected patient-prosthesis mismatch (PPM) rate calculated using the ideal body weight of patients can theoretically show a significant improvement compared to the actual rate of PPM conventionally calculated with the actual body weight of patients. Methods: We retrospectively analysed 2827 patients who underwent aortic valve replacement over 10 years. The rate of PPM was evaluated by measuring the iEOA using the body weight of the patients at the time of the operation and their ideal body weight. The difference in PPM rate was compared using the chi-square test; additionally, a P value < 0.05 was considered significant. Results: We observed a projected PPM rate of 50.2% with a moderate PPM of 45% and a severe PPM of 5.2% when the real body weight of the patients at the time of their operation was included in the calculus. Simulating a BMI of 22 for all patients, the rates of moderate and severe PPM decreased to 43.8% and 0.5%, respectively (P < 0.001). When simulating a lower BMI at 21, 20, and 19, there was a further significant reduction in moderate PPM at 38.8%, 33.4%, and 26.8%, respectively, and severe PPM at 0.2% and 0.1%, respectively (P < 0.001). Conclusions A significant reduction in post-aortic valve replacement PPM was predicted when the ideal body weight of the patient was used instead of actual body weight, suggesting that pre- and postoperative weight loss programmes should be part of the strategy to reduce PPM.

Article information

Section
Articles
Submitted
May 2, 2024
Accepted
June 11, 2024
Published
June 15, 2024
Corresponding author
Mirko Muretti
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