Open Access Article March 30, 2025

10 Pages

Long-Term Outcomes of Native Infective Endocarditis After Surgery: A Single-Centre Experience

Authors

Jeremy Cheong1,* , Syed Al-nahian2 , Omowumi Folaranmi3 , Andrew Owens4 , Andrew Goodwin5 , Mazyar Kanani6 , Ralph White7 , Danai Karamanou8 , Stuart Grant9 , Enoch Akowuah10

  1. School of Medicine, Newcastle University, Newcastle Upon Tyne
  2. Cardiothoracic Surgery, James Cook University Hospital, Middlesbrough
  3. School of Medicine, Newcastle University, Newcastle Upon Tyne
  4. Cardiothoracic Surgery, James Cook University Hospital, Middlesbrough
  5. Cardiothoracic Surgery, James Cook University Hospital, Middlesbrough
  6. Cardiothoracic Surgery, James Cook University Hospital, Middlesbrough
  7. Cardiothoracic Surgery, James Cook University Hospital, Middlesbrough
  8. Cardiothoracic Surgery, James Cook University Hospital, Middlesbrough
  9. School of Medicine, Newcastle University, Newcastle Upon Tyne
  10. School of Medicine, Newcastle University, Newcastle Upon Tyne
  11. * Author to whom correspondence should be addressed.

Journal of Heart Valve Disease Innovation 2025, 30(1), 7-16; https://doi.org/10.36923/jhvd.v30i1.247

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Abstract

Objective: Infective endocarditis requires prompt recognition and treatment due to its high mortality and morbidity rates. Few studies compare long-term patient outcomes after mitral and aortic valve endocarditis surgery. Hence, we aim to assess this in our cohort. Methods: We included adult patients aged 18 and above who underwent surgery between April 2011 and April 2021 for first-time native aortic or mitral valve endocarditis in our study. Patients were followed up until July 2024. Results: 94 patients were included in our study. Streptococcus was the most common bacterial species causing infective endocarditis and was more prevalent in the aortic group than the mitral group. Conversely, Staphylococci were more common in the mitral group. Patients undergoing mitral valve surgery had longer bypass and cross-clamp times compared to the aortic group. There was no statistical difference between aortic valve (AV) and mitral valve (MV) endocarditis in early post-operative re-exploration rates, post-operative cerebrovascular accidents (CVA), or post-operative dialysis. Patients with AV and MV endocarditis had comparable in-hospital and 1-year post-surgery mortality rates. Although the mortality rate for aortic valve endocarditis was higher at both 5-year and 8-year follow-ups, it was not statistically significant. Conclusions: Despite some differences in peri-operative variables, there was no significant difference in short- and long-term mortality rates after aortic and mitral valve endocarditis surgery.

Article information

Keywords
Native Infective EndocarditisAdult PatientsPost-OperativeLong-Term OutcomeMortality
Section
Articles
Issue
Vol. 30 No. 1 (2025)
Submitted
December 2, 2024
Accepted
February 14, 2025
Published
March 30, 2025
Corresponding author
Jeremy Cheong
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